Predicting whole vertebral body strength from bone mineral density assessed via DXA and microarchitecture assessed via micro-CT
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چکیده
Bone and Joint Research Laboratory, SA Pathology and Hanson Institute, Adelaide, South Australia, Australia. Discipline of Anatomy and Pathology, University of Adelaide, Adelaide, South Australia, Australia. School of Physiotherapy, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia. School of Mechanical Engineering, The University of Adelaide, Adelaide, South Australia, Australia, Department of Medicine, University of Melbourne, Victoria, Australia Bone & Mineral Service, Royal Melbourne Hospital, Melbourne, Victoria, Australia. Senior author [email protected]
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Failure strength of human vertebrae: prediction using bone mineral density measured by DXA and bone volume by micro-CT.
Significant relationships exist between areal bone mineral density (BMD) derived from dual energy X-ray absorptiometry (DXA) and bone strength. However, the predictive validity of BMD for osteoporotic vertebral fractures remains suboptimal. The diagnostic sensitivity of DXA in the lumbar spine may be improved by assessing BMD from lateral-projection scans, as these might better approximate the ...
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